Genicunolide A, B and C: three new triterpenoids from Euphorbia geniculata

• Alia Farozi,
• Javid A. Banday and
• Shakeel A. Shah

Beilstein J. Org. Chem. 2015, 11, 2707–2712, doi:10.3762/bjoc.11.291

• friedelinol (5), were isolated from the aerial parts of Euphorbia geniculata. They were characterized as 1β-acetoxy-3β-hydroxy-11α,12α-oxidotaraxer-14-ene, 1β,3β-diacetoxy-21α-hydroxy-11α,12α-oxidotaraxer-14-ene and 3β,9α,20α-trihydroxy-Ψ-taraxast-5-ene, respectively, by spectral and chemical methods

• . Keywords: Euphorbiaceae; Euphorbia geniculata; friedelin; friedelinol; genicunolide A; B; C; pentacyclic triterpenoids; Introduction Euphorbia (Euphorbiaceae) is a very large and diverse genus of flowering plants comprising of about 2,000 members and is found all over the world, ranging from short annual

• -3β,25-diol [21]. In addition, nor-isoprenoids and coumarins have also been reported from few species of Euphorbia [22][23][24]. Euphorbia geniculata Orteg. [25][26], is a wild weed found in the Jammu region of India [27]. The plant is locally used for the treatment of bacterial infections and